What is the Molecular Weight of Glucosamine Hydrochloride? Key Specifications
For overseas buyers sourcing glucosamine hydrochloride, batch consistency and molecular weight are critical to formulation success. Glucosamine hydrochloride (Glucosamine HCl) is a widely used joint health ingredient, typically with a molecular weight of approximately 215.63 g/mol. This article breaks down the key specifications, production considerations, and application guidance to help you make informed purchasing decisions.
Why Molecular Weight Matters for Glucosamine Hydrochloride
When you are evaluating glucosamine hydrochloride suppliers, molecular weight is one of the first parameters to verify. The molecular weight of glucosamine hydrochloride is around 215.63 g/mol. This value is derived from its chemical formula (C6H13NO5·HCl) and is consistent across all pharmaceutical and food-grade sources. A consistent molecular weight ensures predictable dissolution rates and bioavailability in finished products, whether you are manufacturing tablets, capsules, or powders.
Sourcing glucosamine HCl with a verified molecular weight helps avoid batch-to-batch variability. This is especially important for overseas buyers who need to maintain strict quality standards across multiple production runs. Beyond Biopharma offers glucosamine hydrochloride with full COA documentation, so you can confirm the molecular weight and other specs before shipment.
How is Glucosamine Hydrochloride Produced?
Glucosamine hydrochloride is typically derived from chitin, a natural polymer found in the shells of crustaceans like shrimp and crab. The production process involves hydrolysis of chitin using hydrochloric acid, followed by purification and crystallization. The result is a white crystalline powder with a molecular weight of about 215.63 g/mol.
During production, key parameters such as pH, temperature, and reaction time are tightly controlled to ensure the final product meets pharmacopoeial standards. Beyond Biopharma uses automated temperature and pH control in its GMP clean workshop, ensuring consistent quality for every batch of glucosamine HCl.
What Are the Key Specifications of Glucosamine Hydrochloride?
Below is a table of common specifications for glucosamine hydrochloride. These values represent typical industry ranges; final specifications should be confirmed via the supplier's Certificate of Analysis (COA).
| Parameter |
Typical Value |
Notes |
| Molecular Weight |
~215.63 g/mol |
Consistent across food and pharma grades |
| Assay (Content) |
≥99.0% |
On dry basis |
| pH (1% solution) |
3.0–5.0 |
Typical industry range |
| Loss on Drying |
≤1.0% |
Moisture content |
| Heavy Metals |
≤10 ppm |
Per USP/EP standards |
| Particle Size |
80–200 mesh |
Customizable |
Note: The above are typical industry ranges. Final values should be verified per COA or sample analysis.
What Applications Use Glucosamine Hydrochloride?
Glucosamine hydrochloride is a versatile ingredient used across several industries. Here are the primary applications and selection guidance:
- Joint Health Supplements: Glucosamine HCl is a core ingredient in joint health formulations, often combined with chondroitin sulfate and hyaluronic acid. Its low molecular weight (~215.63 g/mol) supports rapid absorption. For a complete joint health solution, consider our premium vegan glucosamine hydrochloride.
- Pharmaceutical Excipients: Used in tablet and capsule formulations, glucosamine HCl requires consistent particle size and purity. Our pharmaceutical-grade product meets strict pharmacopoeial standards.
- Food and Beverage: As a functional ingredient in fortified foods and drinks, glucosamine HCl must be highly soluble and have a neutral taste. Food-grade options are available.
- Cosmetic and Personal Care: In topical creams and serums, glucosamine HCl supports skin health. Cosmetic-grade material with fine particle size is recommended.
For each application, the molecular weight remains constant, but other parameters like particle size and purity may need adjustment. Beyond Biopharma offers three grades (food, pharmaceutical, cosmetic) to match your specific needs.
Why Choose Beyond Biopharma for Glucosamine Hydrochloride?
Beyond Biopharma is a Shanghai-based manufacturer with over 10 years of experience in the food-ingredient industry. Our products are exported to more than 50 countries. We produce glucosamine hydrochloride in a GMP clean workshop with fully automatic production lines, ensuring consistent molecular weight and purity across all batches.
Our facility has an annual capacity of approximately 3,000 MT for collagen and 5,000 MT for gelatin, and we apply the same rigorous quality standards to our joint health ingredients. We hold ISO 9001 certification, are US FDA registered, and select products carry Halal or Kosher certifications. Our in-house lab performs heavy-metal and microbiological testing, and our dedicated QA/QC team ensures every shipment meets your specifications.
We also offer free samples and formulation support. Whether you need glucosamine HCl for food, pharmaceutical, or cosmetic applications, we can provide custom bulk supply and OEM services. For related ingredients, explore our halal and kosher verified fish gelatin or fish collagen peptide for skin health supplements.
Frequently Asked Questions About Glucosamine Hydrochloride
What is the exact molecular weight of glucosamine hydrochloride?
The molecular weight of glucosamine hydrochloride is approximately 215.63 g/mol. This value is based on its chemical formula C6H13NO5·HCl and is consistent across all reputable suppliers.
How does molecular weight affect glucosamine HCl performance?
A consistent molecular weight ensures predictable solubility and bioavailability. Glucosamine HCl with a molecular weight around 215.63 g/mol dissolves readily in water, making it suitable for tablets, capsules, and liquid formulations.
Is glucosamine hydrochloride vegan-friendly?
Standard glucosamine HCl is derived from crustacean shells, so it is not vegan. However, Beyond Biopharma offers a premium vegan glucosamine hydrochloride sourced from non-animal origins for plant-based formulations.
What certifications should I look for when buying glucosamine HCl?
Look for ISO 9001, FDA registration, and third-party testing for heavy metals and microbiological contaminants. Halal and Kosher certifications may also be required depending on your target market.
Can I get a sample of glucosamine hydrochloride before placing a bulk order?
Yes, Beyond Biopharma offers free samples for quality evaluation. Simply provide your application details and target specifications, and we will send a representative sample along with the COA.
How do I store glucosamine hydrochloride?
Store in a cool, dry place away from direct sunlight. Keep the container tightly sealed to prevent moisture absorption. Proper storage ensures the molecular weight and purity remain stable.
Request a Quote and Free Sample
To ensure you receive the right glucosamine hydrochloride for your application, please provide the following details when contacting us:
- Intended application (food, pharmaceutical, cosmetic)
- Required grade (food, pharma, cosmetic)
- Quantity or MOQ
- Target specifications (molecular weight, particle size, certifications)
- Destination country
Beyond Biopharma will send free samples and a competitive quote based on your requirements. We support custom bulk supply and formulation/OEM services. Contact us today to start your evaluation.
The molecular weight of glucosamine hydrochloride is a key specification that ensures product consistency and performance. By partnering with a reliable manufacturer like Beyond Biopharma, you can secure a high-quality ingredient that meets your exact needs.
User Comments
Service Experience Sharing from Real Customers
Jack
Quality Control AnalystAs someone who works in pharmaceutical testing, I appreciate products that provide precise specifications. The molecular weight info for this glucosamine HCl was spot-on (215.63 g/mol, right?), which made our lab calculations straightforward. The batch consistency has been reliable over six months of use.
Jacqueline
Senior Formulation ChemistI've been sourcing raw materials for nutraceutical formulations for 12 years. This supplier's documentation saved me hours of cross-referencing – having the exact molecular weight of glucosamine hydrochloride (C6H14ClNO5) clearly listed prevented a potential dosing error in our new joint health line. Small detail, big impact.
Jackson
Veterinary NutritionistOrdered this for compounding supplements for older dogs. The molecular weight specification helped me accurately adjust dosages for different weight classes. Powder mixes well, though I wish the COA included more impurity profiles. Still, solid for clinical use.
Jake
Supplement Store OwnerHonestly, most customers don't ask about molecular weights, but as a former biochemistry major, I check these things. The fact that they openly provide the glucosamine HCl molecular weight (and it matches my Merck Index) tells me they're transparent. My wholesale clients trust our recommendations more because we dig into these details.